Via Kolda and Tambacounda to Bamako.
There are through buses from Dakar to Bamako (30? hours) but at the moment they are not allowed to pick up passengers in Tambacounda. Its best to go to the Gare Routiere Tambacounda in the early morning, take a Sept Place (shared taxi) to the border, 5000 CFA about 4 hours, take then a taxi (the stamp out of Senegal is not done at a distance from the border) and tell the driver you want to go by bus to Bamako, he will bring you to a bus stand before the Mali border, 1000 CFA. The bus from there to Bamako is 15000 CFA and about 18 hours.
The Niaré settled at the banks of the river and founded there by the end of the 16th Century the city. It became a trading center and had before the arrival of the French in 1883 about 600 residents. In 1908 It became the capital of the French provinces of Upper Senegal and Niger in 1908 . After gaining independence from France in 1960 it became the capital of Mali.